Nanoengineering for Mechanobiology

March 24th - 27th 2019, Camogli, Genova, Italy

4th international symposium on Nanoengineering for Mechanobiology (N4M). Three vibriant days to enjoy science in a picturesque environment with passionate scientists from over the world and the participation of leading companies in the field.

Organizers and Institutional support
Sponsors
About

About the symposium

Following the tradition of the first three editions, the Nanoengineering for Mechanobiology symposium will be organized at the beginning of Spring 2019, from March 24th to 27th in the picturesque fishermen village of Camogli, located on the shore of the Ligurian sea, close to the city of Genova, Italy. This year EMPA Zürich and CNR Genova will partner with LENS, the European Laboratory for Non-Linear Spectroscopy of Florence to bring together scientists from all over the world, interested in sharing ideas on new and upcoming technologies and applications towards a deeper understanding of how the mechanical environment is shaping the function of cells and tissues.

The upcoming edition of the meeting is expected to host a stimulating multidisciplinary environment, with researchers belonging to different areas, from physics and engineering to biology and medicine, but sharing a common scientific interest. The main methodological focus will be posed on the application of advanced microscopy and spectroscopy approaches to follow the dynamics and measure the mechanical properties of single molecules and cells. Moreover, the scientific sessions will be flanked by a technological exhibit involving world-leading companies and high tech startups interested in presenting their solutions and services for the growing community of mechanobiology.

We suggest to have a look at the list of keynote speakers and register to the conference or, if you are still planning your next year activities, subscribe to the N4M Google Group

See you soon in Camogli!

Overview

Overview

The conference will start on Sunday evening and the welcome activities will be held in Genova, to provide a simpler logistics for the attendees to reach the venue, and to have the possibility to have a walk in this beautiful city that has recently been injured by the collapse of one of its symbols, the Morandi bridge. After the welcome dinner, all the participants will be transferred to the fishermen village of Camogli to enjoy the rest of the conference. The last day, the conference will terminate after lunch and a shuttle will be organized to reach the Genova airport.
  • Sunday 24/03
    Genova
    17:00 - 22:00
  • Registration and opening
  • Welcome lecture
  • Get together dinner
  • Monday 24/03
    Camogli
    9:00 - 19:00
  • Scientific session 1
  • Lunch and poster session
  • Scientific session 2
  • Tuesday 24/03
    Camogli
    9:00 - 19:00
  • LENS special session 3
  • Lunch and poster session
  • LENS special session 4
  • Wednesday 24/03
    Camogli
    9:00 - 14:00
  • Scientific session 5
  • Lunch and symposium closure
See the full program for more details and subscribe to the N4M Google Group to remain updated.
Sponsors

Sponsors

Mad City Labs
Olympus
Lumicks
FABCrea
Physik Instrumente (PI)
Keynote speakers

Keynote Speakers

Felix Rico
Université de Aix-Marseille, France

We develop and apply high-speed atomic force microscopy (AFM and high-speed AFM) to unravel the physics behind biological systems. Our research is based on force spectroscopy approaches to determine how single molecules and living cells response to mechanical forces.

External website
Oliver Friedrich
Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany

OF and his team develop and engineer new biomechatronics solutions for highly automated or high-content experimentation in the field of mechanobiology, among which the IsoStretcher, MyoRobot and the MechaMorph are some recent developments. Applying those systems to study involvement of mechanosensitive channels in cardiac tissue or axial biomechanical compliance of skeletal muscle fibres in various disease models represent some of the current research topics covered.

External website
Michele De Luca
Università di Modena e Reggio Emilia, Italy

Michele De Luca has dedicated most of his scientific activities to translational medicine. He is recognised as leading scientist in human squamous epithelial stem cell biology aimed at the development of epithelial stem cell-mediated cell therapy and gene therapy.

External website
Sandra Citi
Université de Genève, Switzerland

The goal of the Citi laboratory is to understand at the molecular level how the apical junctional complex of vertebrate epithelial cells controls epithelial function, morphogenesis, differentiation and proliferation.

External website
Peter Kohl
Universitäts-Herzzentrum Freiburg, Germany

Research interests: Mechano-electric coupling in the cardio-vascular system, Hetero-cellular cross-talk and roles of non-excitable cells in cardiac biophysics, Integrated wet-and-dry studies of cardio-vascular structure and function, Method development, imaging, auto-regulation.

External website
Edoardo Mazza
ETH Zürich, Switzerland

Professor Mazza's research deals with experimental continuum mechanics, applied for the solution of challenging problems in engineering and medicine. Novel experimental techniques are developed for the multiscale characterization of the mechanical reponse of structures and materials.

External website
Aurélien Roux
Université de Genève, Switzerland

My research focus is on the mechanical and dynamic properties of lipids and proteins involved in membrane traffic. Specifically, how do these properties produce efficient membrane deformation, lipid and protein sorting within traffic intermediates, and fission of separating membranes?

External website
Manuel Salmeron-Sanchez
University of Glasgow, UK

Material-based strategies to engineer tissue repair and regeneration, and to understand pathological conditions such as cancer. His multidisciplinary group designs microenvironments to simulate the complex spatio-temporal cues of the extracellular matrix, including viscoelastic substrates and 3D protein-based hydrogels that control integrin and growth factor receptor signalling.

External website
Kristian Franze
University of Cambridge, UK

We are taking an interdisciplinary approach to investigate how cellular forces, local cell and tissue compliance and cellular mechanosensitivity contribute to CNS development and disease. Methods we are exploiting include atomic force microscopy, traction force microscopy, custom-built simple and complex compliant cell culture substrates, optical microscopy including confocal laser scanning microscopy and cell biological techniques.

External website
Charles Cox
Victor Chang Cardiac Research Institute, Sydney, Australia

The newly formed Cox Lab is focused on the molecular workings of mechanically-gated ion channels. In particular how they are regulated by the lipid environment and structural scaffold proteins. This includes trying to understand the bidirectional flow of information between these channels and the cytoskeleton and their downstream signaling effectors.

External website
Program

Program

  • 24/03 17:00-18:00
  • Registration
  • 24/03 18:00-19:00
    Opening session
  • Aldo Ferrari and Massimo Vassalli

    Organizing committee

    Introduction and welcome

  • Michele De Luca

    Università di Modena e Reggio Emilia, Italy

    Epithelial stem cells in cell and gene therapy

  • 24/03 19:30-22:00
  • Get together dinner
  • 25/03 9:00-13:00
    Scientific session 1
  • Felix Rico

    Université de Aix-Marseille, France

    Molecular to cellular mechanics probed by atomic force microscopy

  • Contributed talk
  • Contributed talk
  • Oliver Friedrich

    Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany

    Pulling the strings - novel biomechatronics feeds for biomechanical studies in cardiac and skeletal muscle

  • Contributed talk
  • Contributed talk
  • 25/03 13:00-15:00
  • Lunch and poster session
  • 25/03 15:00-19:00
    Scientific session 2
  • Charles Cox

    Victor Chang Cardiac Research Institute, Sydney, Australia

    Mechanosensitive Piezo channels: bidirectional feedback with lipids and the cytoskeleton

  • Contributed talk
  • Contributed talk
  • Manuel Salmeron-Sanchez

    University of Glasgow, UK

    Engineering the cellular microenvironment with biomaterials: mechanics, growth factors and beyond

  • Contributed talk
  • Contributed talk
  • 26/03 9:00-13:00
    LENS special session 1
  • Sandra Citi

    Université de Genève, Switzerland

    Molecular mechanisms of mechanostranduction at apical cell-cell junctions

  • Contributed talk
  • Contributed talk
  • Peter Kohl

    Universitäts-Herzzentrum Freiburg, Germany

    Cardiac Mechano-Sensitivity: from Pipette to Patient

  • Contributed talk
  • Contributed talk
  • 26/03 13:00-15:00
  • Lunch and poster session
  • 26/03 15:00-19:00
    LENS special session 2
  • Aurélien Roux

    Université de Genève, Switzerland

    Buckling of epithelium growing under spherical confinement

  • Contributed talk
  • Contributed talk
  • Kristian Franze

    University of Cambridge, UK

  • Contributed talk
  • Contributed talk
  • 27/03 9:00-13:00
    Final scientific session
  • Edoardo Mazza

    ETH Zürich, Switzerland

    Biomechanics and mechanobiology of soft collagenous tissue: some novel insights from multiscale mechanical experiments

  • Contributed talk
  • Contributed talk
  • To be defined

    ...

  • Contributed talk
  • Contributed talk
  • 25/03 13:00-15:00
  • Farewell Lunch
Registration

Registration

The Nanoengineering for Mechanobiology symposium is organized in Camogli, a nice fishermen village near Genova, with the aim to bring together for three days junior and senior scientists passionate for the field of Mechanobiology. To enhance the interaction among the attendees, the core activities of the conference are organized inside the Hotel Cenobio dei Dogi which is also the accommodation for the participants. To simplify the logistics of the arrival and to have a feeling of the city of Genova, the opening lecture, registration and welcome dinner will be held in the center of Genova.

The first round of registration to the symposium is open till 08/12/2018. After that date all applicants will be notified about the outcome of the application (either poster or oral participation) and the payment of the fees will be requested before December 31st. The symposium is targeted to a small audience and typically no more of 80 attendees will be allowed to participate. In case of remaining free seats after the first round, a second application session will be opened in January, only for poster and simple attendees.

The conference registration pack includes:

  • Conference material
  • 3 nights at the conference hotel
  • All lunches and coffee breaks
  • Welcome dinner

Participation fees are set to 500€, including all the above listed items. To register, click on the button below, register and fill the forms.

Register HERE

Privacy note: your data will be collected for the sole purpose of the registration and participation to the N4M meeting. Your name, email and data will be shared only with the participants and the service providers involved in the management of the conference, and for the specific need. All data will be deleted after the end of the conference and your email will be included in the N4M Google Group to get future info on the conference (with possibility to unsubscribe at any moment).

Organization

Organization

Massimo Vassalli
Institute of Biophysics
National Research Council
massimo.vassalli@cnr.it

Marco Capitanio, Leonardo Sacconi, Riccardo Cicchi
LENS, European Laboratory for Non-Linear Spectroscopy, Firenze, Italy

Aldo Ferrari
Empa Dübendorf, Switzerland
aldo.ferrari@empa.ch

Venue
The symposium will be held at

Hotel Cenobio dei Dogi

Via Nicolò Cuneo, 34
16032 Camogli Genova, Italy
cenobio.it

By train

The Camogli S.Fruttuoso station is 2 minutes walk from the Hotel and directly connected to the national railway network. Find timetables and connections at the Trenitalia website

By car

Have a look at the directions provided by the Hotel or follow any navigation system. The Hotel Cenobio dei Dogi provides free parking for all attendees staying at the Hotel.

By plane

The nearest airport is Genova Cristoforo Colombo, which is internationally connected to Paris (Air France), Munich (Lufthansa), London (Ryanair and BA), Barcelona (Flyvalan), Bruxelles (Flyvalan), Amsterdam (KLM), Zurich (Flyvalan) and nationally to the international hub Fiumicino in Rome. The airport is connected via a shuttle service to the Genova Brignole train station (volabus, check the timetable) where a train to Camogli departs every half an hour (timetable and tickets).